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Unilateral lichen planus with Blaschko line distribution: A case report
BACKGROUND: Lichen planus (LP) with distribution of lesions along Blaschko’s lines is a rare entity, accounting for 0.24%-0.62% of all patients. Unilateral distribution of lesions in arm, leg, trunk, and waist is even less common. Approximately 10% of patients with LP manifest nail lesions. CASE SUM...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453370/ https://www.ncbi.nlm.nih.gov/pubmed/36157808 http://dx.doi.org/10.12998/wjcc.v10.i24.8679 |
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author | Dong, Shuai Zhu, Wen-Jing Xu, Meng Zhao, Xue-Qi Mou, Yan |
author_facet | Dong, Shuai Zhu, Wen-Jing Xu, Meng Zhao, Xue-Qi Mou, Yan |
author_sort | Dong, Shuai |
collection | PubMed |
description | BACKGROUND: Lichen planus (LP) with distribution of lesions along Blaschko’s lines is a rare entity, accounting for 0.24%-0.62% of all patients. Unilateral distribution of lesions in arm, leg, trunk, and waist is even less common. Approximately 10% of patients with LP manifest nail lesions. CASE SUMMARY: A 20-year-old woman presented to our department with polygonal, purpuric, flat-topped papules over the right arm, right leg, and right side of trunk and waist for the last 5 mo. The patient initially developed nail deformation in the left middle finger with no obvious cause, followed by development of blue-purple and red maculopapular rash with pruritus. During the disease course, the skin lesions aggravated and spread to several segments due to scratching. The lesions showed unilateral distribution along the Blaschko’s lines. The diagnosis of LP along Blaschko’s lines was established based on dermoscopy and skin biopsy. Her cutaneous lesions considerably improved after 4-wk treatment with intramuscular glucocorticoid, oral acitretin, topical glucocorticoid, and retinoids. CONCLUSION: Cases of LP involving multiple segments of the body along the Blaschko’s lines with nail damage are rare. |
format | Online Article Text |
id | pubmed-9453370 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-94533702022-09-23 Unilateral lichen planus with Blaschko line distribution: A case report Dong, Shuai Zhu, Wen-Jing Xu, Meng Zhao, Xue-Qi Mou, Yan World J Clin Cases Case Report BACKGROUND: Lichen planus (LP) with distribution of lesions along Blaschko’s lines is a rare entity, accounting for 0.24%-0.62% of all patients. Unilateral distribution of lesions in arm, leg, trunk, and waist is even less common. Approximately 10% of patients with LP manifest nail lesions. CASE SUMMARY: A 20-year-old woman presented to our department with polygonal, purpuric, flat-topped papules over the right arm, right leg, and right side of trunk and waist for the last 5 mo. The patient initially developed nail deformation in the left middle finger with no obvious cause, followed by development of blue-purple and red maculopapular rash with pruritus. During the disease course, the skin lesions aggravated and spread to several segments due to scratching. The lesions showed unilateral distribution along the Blaschko’s lines. The diagnosis of LP along Blaschko’s lines was established based on dermoscopy and skin biopsy. Her cutaneous lesions considerably improved after 4-wk treatment with intramuscular glucocorticoid, oral acitretin, topical glucocorticoid, and retinoids. CONCLUSION: Cases of LP involving multiple segments of the body along the Blaschko’s lines with nail damage are rare. Baishideng Publishing Group Inc 2022-08-26 2022-08-26 /pmc/articles/PMC9453370/ /pubmed/36157808 http://dx.doi.org/10.12998/wjcc.v10.i24.8679 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Case Report Dong, Shuai Zhu, Wen-Jing Xu, Meng Zhao, Xue-Qi Mou, Yan Unilateral lichen planus with Blaschko line distribution: A case report |
title | Unilateral lichen planus with Blaschko line distribution: A case report |
title_full | Unilateral lichen planus with Blaschko line distribution: A case report |
title_fullStr | Unilateral lichen planus with Blaschko line distribution: A case report |
title_full_unstemmed | Unilateral lichen planus with Blaschko line distribution: A case report |
title_short | Unilateral lichen planus with Blaschko line distribution: A case report |
title_sort | unilateral lichen planus with blaschko line distribution: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453370/ https://www.ncbi.nlm.nih.gov/pubmed/36157808 http://dx.doi.org/10.12998/wjcc.v10.i24.8679 |
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