Secondary sclerosing cholangitis after critical COVID-19: Three case reports

BACKGROUND: The global coronavirus disease 2019 (COVID-19) pandemic has caused more than 5 million deaths. Multiorganic involvement is well described, including liver disease. In patients with critical COVID-19, a new entity called "post-COVID-19 cholangiopathy" has been described. CASE SU...

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Autores principales: Mayorquín-Aguilar, Juan M, Lara-Reyes, Aldo, Revuelta-Rodríguez, Luis Alberto, Flores-García, Nayelli C, Ruiz-Margáin, Astrid, Jiménez-Ferreira, Marco Antonio, Macías-Rodríguez, Ricardo Ulises
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453459/
https://www.ncbi.nlm.nih.gov/pubmed/36157873
http://dx.doi.org/10.4254/wjh.v14.i8.1678
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author Mayorquín-Aguilar, Juan M
Lara-Reyes, Aldo
Revuelta-Rodríguez, Luis Alberto
Flores-García, Nayelli C
Ruiz-Margáin, Astrid
Jiménez-Ferreira, Marco Antonio
Macías-Rodríguez, Ricardo Ulises
author_facet Mayorquín-Aguilar, Juan M
Lara-Reyes, Aldo
Revuelta-Rodríguez, Luis Alberto
Flores-García, Nayelli C
Ruiz-Margáin, Astrid
Jiménez-Ferreira, Marco Antonio
Macías-Rodríguez, Ricardo Ulises
author_sort Mayorquín-Aguilar, Juan M
collection PubMed
description BACKGROUND: The global coronavirus disease 2019 (COVID-19) pandemic has caused more than 5 million deaths. Multiorganic involvement is well described, including liver disease. In patients with critical COVID-19, a new entity called "post-COVID-19 cholangiopathy" has been described. CASE SUMMARY: Here, we present three patients with severe COVID-19 that subsequently developed persistent cholestasis and chronic liver disease. All three patients required intensive care unit admission, mechanical ventilation, vasopressor support, and broad spectrum antibiotics due to secondary infections. Liver transplant protocol was started for two of the three patients. CONCLUSION: Severe COVID-19 infection should be considered a potential risk factor for chronic liver disease and liver transplantation.
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spelling pubmed-94534592022-09-23 Secondary sclerosing cholangitis after critical COVID-19: Three case reports Mayorquín-Aguilar, Juan M Lara-Reyes, Aldo Revuelta-Rodríguez, Luis Alberto Flores-García, Nayelli C Ruiz-Margáin, Astrid Jiménez-Ferreira, Marco Antonio Macías-Rodríguez, Ricardo Ulises World J Hepatol Case Report BACKGROUND: The global coronavirus disease 2019 (COVID-19) pandemic has caused more than 5 million deaths. Multiorganic involvement is well described, including liver disease. In patients with critical COVID-19, a new entity called "post-COVID-19 cholangiopathy" has been described. CASE SUMMARY: Here, we present three patients with severe COVID-19 that subsequently developed persistent cholestasis and chronic liver disease. All three patients required intensive care unit admission, mechanical ventilation, vasopressor support, and broad spectrum antibiotics due to secondary infections. Liver transplant protocol was started for two of the three patients. CONCLUSION: Severe COVID-19 infection should be considered a potential risk factor for chronic liver disease and liver transplantation. Baishideng Publishing Group Inc 2022-08-27 2022-08-27 /pmc/articles/PMC9453459/ /pubmed/36157873 http://dx.doi.org/10.4254/wjh.v14.i8.1678 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Mayorquín-Aguilar, Juan M
Lara-Reyes, Aldo
Revuelta-Rodríguez, Luis Alberto
Flores-García, Nayelli C
Ruiz-Margáin, Astrid
Jiménez-Ferreira, Marco Antonio
Macías-Rodríguez, Ricardo Ulises
Secondary sclerosing cholangitis after critical COVID-19: Three case reports
title Secondary sclerosing cholangitis after critical COVID-19: Three case reports
title_full Secondary sclerosing cholangitis after critical COVID-19: Three case reports
title_fullStr Secondary sclerosing cholangitis after critical COVID-19: Three case reports
title_full_unstemmed Secondary sclerosing cholangitis after critical COVID-19: Three case reports
title_short Secondary sclerosing cholangitis after critical COVID-19: Three case reports
title_sort secondary sclerosing cholangitis after critical covid-19: three case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453459/
https://www.ncbi.nlm.nih.gov/pubmed/36157873
http://dx.doi.org/10.4254/wjh.v14.i8.1678
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