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Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane

[Image: see text] A promising technique for repairing necrotic mucosa of human organs has emerged, in which composite films are used to replace human mucosa. In this work, neutral alpha-amylase corrosion solution with a concentration of 0.40 mg/mL and hydrochloric acid corrosion solution at pH 0.9 w...

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Autores principales: Yuan, Haoqiang, Zhang, Yongqiang, Xue, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453966/
https://www.ncbi.nlm.nih.gov/pubmed/36092637
http://dx.doi.org/10.1021/acsomega.2c02478
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author Yuan, Haoqiang
Zhang, Yongqiang
Xue, Zhenhua
author_facet Yuan, Haoqiang
Zhang, Yongqiang
Xue, Zhenhua
author_sort Yuan, Haoqiang
collection PubMed
description [Image: see text] A promising technique for repairing necrotic mucosa of human organs has emerged, in which composite films are used to replace human mucosa. In this work, neutral alpha-amylase corrosion solution with a concentration of 0.40 mg/mL and hydrochloric acid corrosion solution at pH 0.9 were used as simulated oral cavity and gastric fluid environments under the condition of human body temperature. The prepared cellulose film and the cellulose water-based polyurethane composite film (the concentration of water-based polyurethane was 90, 92, 94, 96, or 98%) were mixed in the simulated environment. The composite membrane had a weaker water swelling property (water swelling degree of 4.32%), weaker surface hydrophilicity (water contact angle of 59.05°), and stronger enzyme activity (1.77 U). This functional film composite material is expected to become an ideal substitute for human mucosa.
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spelling pubmed-94539662022-09-09 Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane Yuan, Haoqiang Zhang, Yongqiang Xue, Zhenhua ACS Omega [Image: see text] A promising technique for repairing necrotic mucosa of human organs has emerged, in which composite films are used to replace human mucosa. In this work, neutral alpha-amylase corrosion solution with a concentration of 0.40 mg/mL and hydrochloric acid corrosion solution at pH 0.9 were used as simulated oral cavity and gastric fluid environments under the condition of human body temperature. The prepared cellulose film and the cellulose water-based polyurethane composite film (the concentration of water-based polyurethane was 90, 92, 94, 96, or 98%) were mixed in the simulated environment. The composite membrane had a weaker water swelling property (water swelling degree of 4.32%), weaker surface hydrophilicity (water contact angle of 59.05°), and stronger enzyme activity (1.77 U). This functional film composite material is expected to become an ideal substitute for human mucosa. American Chemical Society 2022-08-22 /pmc/articles/PMC9453966/ /pubmed/36092637 http://dx.doi.org/10.1021/acsomega.2c02478 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Yuan, Haoqiang
Zhang, Yongqiang
Xue, Zhenhua
Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane
title Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane
title_full Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane
title_fullStr Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane
title_full_unstemmed Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane
title_short Preliminary Study on a Biocompatible Cellulose Waterborne Polyurethane Composite Membrane
title_sort preliminary study on a biocompatible cellulose waterborne polyurethane composite membrane
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9453966/
https://www.ncbi.nlm.nih.gov/pubmed/36092637
http://dx.doi.org/10.1021/acsomega.2c02478
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