Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane Fusion

[Image: see text] The HIV envelope protein gp160 comprises two subunits, gp120 and gp41, responsible for receptor binding and membrane fusion during viral entry, respectively. In the course of the membrane fusion process, gp41 undergoes a conformational change, leading to the formation of a six-heli...

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Detalles Bibliográficos
Autores principales: Klug, Yoel A., Schwarzer, Roland, Ravula, Thirupathi, Rotem, Etai, Ramamoorthy, Ayyalusamy, Shai, Yechiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454089/
https://www.ncbi.nlm.nih.gov/pubmed/35994087
http://dx.doi.org/10.1021/acs.biochem.2c00372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454089/
https://www.ncbi.nlm.nih.gov/pubmed/35994087
http://dx.doi.org/10.1021/acs.biochem.2c00372

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