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Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane Fusion
[Image: see text] The HIV envelope protein gp160 comprises two subunits, gp120 and gp41, responsible for receptor binding and membrane fusion during viral entry, respectively. In the course of the membrane fusion process, gp41 undergoes a conformational change, leading to the formation of a six-heli...
Autores principales: | Klug, Yoel A., Schwarzer, Roland, Ravula, Thirupathi, Rotem, Etai, Ramamoorthy, Ayyalusamy, Shai, Yechiel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454089/ https://www.ncbi.nlm.nih.gov/pubmed/35994087 http://dx.doi.org/10.1021/acs.biochem.2c00372 |
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