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A transcriptomic map of EGFR-induced epithelial-to-mesenchymal transition identifies prognostic and therapeutic targets for head and neck cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) is both a driver oncogene and a therapeutic target in advanced head and neck squamous cell carcinoma (HNSCC). However, response to EGFR treatment is inconsistent and lacks markers for treatment prediction. This study investigated EGFR-induced epith...

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Detalles Bibliográficos
Autores principales:	Schinke, Henrik, Shi, Enxian, Lin, Zhongyang, Quadt, Tanja, Kranz, Gisela, Zhou, Jiefu, Wang, Hongxia, Hess, Julia, Heuer, Steffen, Belka, Claus, Zitzelsberger, Horst, Schumacher, Udo, Genduso, Sandra, Riecken, Kristoffer, Gao, Yujing, Wu, Zhengquan, Reichel, Christoph A., Walz, Christoph, Canis, Martin, Unger, Kristian, Baumeister, Philipp, Pan, Min, Gires, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454230/ https://www.ncbi.nlm.nih.gov/pubmed/36076232 http://dx.doi.org/10.1186/s12943-022-01646-1

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