Cargando…
Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice
[Image: see text] The portfolio of SARS-CoV-2 small molecule drugs is currently limited to a handful that are either approved (remdesivir), emergency approved (dexamethasone, baricitinib, paxlovid, and molnupiravir), or in advanced clinical trials. Vandetanib is a kinase inhibitor which targets the...
Autores principales: | Puhl, Ana C., Gomes, Giovanni F., Damasceno, Samara, Fritch, Ethan J., Levi, James A., Johnson, Nicole J., Scholle, Frank, Premkumar, Lakshmanane, Hurst, Brett L., Lee-Montiel, Felipe, Veras, Flavio P., Batah, Sabrina S., Fabro, Alexandre T., Moorman, Nathaniel J., Yount, Boyd L., Dickmander, Rebekah J., Baric, Ralph S., Pearce, Kenneth H., Cunha, Fernando Q., Alves-Filho, José C., Cunha, Thiago M., Ekins, Sean |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454268/ https://www.ncbi.nlm.nih.gov/pubmed/36097511 http://dx.doi.org/10.1021/acsomega.2c02794 |
Ejemplares similares
-
Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice
por: Puhl, Ana C., et al.
Publicado: (2021) -
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms
por: Puhl, Ana C., et al.
Publicado: (2020) -
Repurposing the Ebola and Marburg Virus Inhibitors
Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity
against SARS-CoV-2 and
Potential Mechanisms
por: Puhl, Ana C., et al.
Publicado: (2021) -
Vandetanib
por: Vozniak, J. Michael, et al.
Publicado: (2012) -
Apoferritin/Vandetanib Association Is Long-Term Stable But Does Not Improve Pharmacological Properties of Vandetanib
por: Jáklová, Kateřina, et al.
Publicado: (2021)