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A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient

Immunoglobulin A vasculitis (IgAV; formerly called Henoch-Schönlein purpura) is a disease commonly seen in children as an immune reaction after a viral infection. It is a small vessel vasculitis characterized by immune complex deposits in various organs throughout the body. It mainly affects the ski...

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Autores principales: Bazigh, Izza, Patel, Etee, Khan, Uzair, Ghalib, Neha, Singh, Aaparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454305/
https://www.ncbi.nlm.nih.gov/pubmed/36106304
http://dx.doi.org/10.7759/cureus.27812
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author Bazigh, Izza
Patel, Etee
Khan, Uzair
Ghalib, Neha
Singh, Aaparna
author_facet Bazigh, Izza
Patel, Etee
Khan, Uzair
Ghalib, Neha
Singh, Aaparna
author_sort Bazigh, Izza
collection PubMed
description Immunoglobulin A vasculitis (IgAV; formerly called Henoch-Schönlein purpura) is a disease commonly seen in children as an immune reaction after a viral infection. It is a small vessel vasculitis characterized by immune complex deposits in various organs throughout the body. It mainly affects the skin, joints, abdomen and kidneys. This presentation is less likely to be seen in adults. In adults, IgAV can be seen due to decreased clearance of immune complexes through the liver. A damaged liver due to alcoholic liver cirrhosis can hinder the clearance of IgA complexes. We present an unusual case of a 42-year-old female who presented with alcoholic liver cirrhosis and ascites and later developed a purpuric rash in her lower extremities.
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spelling pubmed-94543052022-09-13 A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient Bazigh, Izza Patel, Etee Khan, Uzair Ghalib, Neha Singh, Aaparna Cureus Internal Medicine Immunoglobulin A vasculitis (IgAV; formerly called Henoch-Schönlein purpura) is a disease commonly seen in children as an immune reaction after a viral infection. It is a small vessel vasculitis characterized by immune complex deposits in various organs throughout the body. It mainly affects the skin, joints, abdomen and kidneys. This presentation is less likely to be seen in adults. In adults, IgAV can be seen due to decreased clearance of immune complexes through the liver. A damaged liver due to alcoholic liver cirrhosis can hinder the clearance of IgA complexes. We present an unusual case of a 42-year-old female who presented with alcoholic liver cirrhosis and ascites and later developed a purpuric rash in her lower extremities. Cureus 2022-08-09 /pmc/articles/PMC9454305/ /pubmed/36106304 http://dx.doi.org/10.7759/cureus.27812 Text en Copyright © 2022, Bazigh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Bazigh, Izza
Patel, Etee
Khan, Uzair
Ghalib, Neha
Singh, Aaparna
A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient
title A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient
title_full A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient
title_fullStr A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient
title_full_unstemmed A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient
title_short A Case of Adult-Onset IgA Vasculitis in a Cirrhotic Patient
title_sort case of adult-onset iga vasculitis in a cirrhotic patient
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454305/
https://www.ncbi.nlm.nih.gov/pubmed/36106304
http://dx.doi.org/10.7759/cureus.27812
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