Cargando…

Qingfei Jiedu decoction inhibits PD-L1 expression in lung adenocarcinoma based on network pharmacology analysis, molecular docking and experimental verification

Objective: We aim at investigating the molecular mechanisms through which the Qingfei Jiedu decoction (QFJDD) regulates PD-L1 expression in lung adenocarcinoma (LUAD). Methods: Bioactive compounds and targets of QFJDD were screened from TCMSP, BATMAN-TCM, and literature. Then, GeneCard, OMIM, PharmG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Junjie, Yang, Hongkuan, Zhu, Lihong, Lou, Yafang, Jin, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454399/ https://www.ncbi.nlm.nih.gov/pubmed/36091822 http://dx.doi.org/10.3389/fphar.2022.897966

Ejemplares similares

Research Advance on Qingfei Paidu Decoction in Prescription Principle, Mechanism Analysis and Clinical Application
por: Ren, Wei, et al.
Publicado: (2021)

Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury
por: Liu, Jiahui, et al.
Publicado: (2023)

Network pharmacology and computer-aided drug design to explored potential targets of Lianhua Qingwen and Qingfei Paidu decoction for COVID-19
por: Li, Liyuan, et al.
Publicado: (2022)

Efficacy and Safety of Qingfei Paidu Decoction for Treating COVID-19: A Systematic Review and Meta-Analysis
por: Wang, Qi, et al.
Publicado: (2021)

Decoding the Mechanism of Huanglian Jiedu Decoction in Treating Pneumonia Based on Network Pharmacology and Molecular Docking
por: Li, Xianhai, et al.
Publicado: (2021)

Molecular mechanisms of Huanglian jiedu decoction on ulcerative colitis based on network pharmacology and molecular docking
por: Yang, Jing, et al.
Publicado: (2022)

Qingfei Jiedu Granules fight influenza by regulating inflammation, immunity, metabolism, and gut microbiota
por: Cui, Xuran, et al.
Publicado: (2022)

Analysis of the Anti-Tumour Effect of Xuefu Zhuyu Decoction Based on Network Pharmacology and Experimental Verification in Drosophila
por: Wang, Sitong, et al.
Publicado: (2022)

Research of the Active Components and Potential Mechanisms of Qingfei Gujin Decoction in the Treatment of Osteosarcoma Based on Network Pharmacology and Molecular Docking Technology
por: Yan, Qingying, et al.
Publicado: (2022)

Exploring the Potential Mechanism of Xiaokui Jiedu Decoction for Ulcerative Colitis Based on Network Pharmacology and Molecular Docking
por: Wang, Bin, et al.
Publicado: (2021)

Huanglian Jiedu Decoction in the Treatment of the Traditional Chinese Medicine Syndrome “Shanghuo”–An Intervention Study
por: Luo, Keke, et al.
Publicado: (2021)

The Anti-Inflammatory and Anti-Pruritus Mechanisms of Huanglian Jiedu Decoction in the Treatment of Atopic Dermatitis
por: Xu, Yubin, et al.
Publicado: (2021)

In Vitro Antibacterial Experiment of Fuzheng Jiedu Huayu Decoction Against Multidrug-Resistant Pseudomonas aeruginosa
por: Xu, Hongri, et al.
Publicado: (2020)

Yiqi Jiedu Huayu Decoction Alleviates Renal Injury in Rats With Diabetic Nephropathy by Promoting Autophagy
por: Xuan, Chen, et al.
Publicado: (2021)

Traditional Chinese Medicine, Qingfei Paidu Decoction and Xuanfei Baidu Decoction, Inhibited Cytokine Production via NF-κB Signaling Pathway in Macrophages: Implications for Coronavirus Disease 2019 (COVID-19) Therapy
por: Li, Yujia, et al.
Publicado: (2021)

Therapeutic Effect and Mechanism of Bushen-Jianpi-Jiedu Decoction Combined with Chemotherapeutic Drugs on Postoperative Colorectal Cancer
por: Yang, Meng-Die, et al.
Publicado: (2021)

New strategies for identifying and masking the bitter taste in traditional herbal medicines: The example of Huanglian Jiedu Decoction
por: Ke, Xiumei, et al.
Publicado: (2022)

Network Pharmacology Interpretation of Fuzheng–Jiedu Decoction against Colorectal Cancer
por: Shi, Hongshuo, et al.
Publicado: (2021)

Qingfei Litan Decoction Against Acute Lung Injury/Acute Respiratory Distress Syndrome: The Potential Roles of Anti-Inflammatory and Anti-Oxidative Effects
por: Diao, Yirui, et al.
Publicado: (2022)

Molecular Mechanism of the Effect of Huanglian Jiedu Decoction on Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking
por: Yin, Bei, et al.
Publicado: (2020)

Network pharmacology and molecular docking analysis on molecular targets and mechanism prediction of Huanglian Jiedu Decoction in the treatment of COVID-19
por: Xinyi, Xu, et al.
Publicado: (2022)

Potential Targets and Mechanisms of Jiedu Quyu Ziyin Decoction for Treating SLE-GIOP: Based on Network Pharmacology and Molecular Docking
por: Li, Jie, et al.
Publicado: (2023)

A Novel Strategy for Decoding and Validating the Combination Principles of Huanglian Jiedu Decoction From Multi-Scale Perspective
por: Wang, Ke-Xin, et al.
Publicado: (2020)

Study on the Molecular Basis of Huanglian Jiedu Decoction Against Atopic Dermatitis Integrating Chemistry, Biochemistry, and Metabolomics Strategies
por: Chen, Jing, et al.
Publicado: (2021)

The interaction of MD-2 with small molecules in huanglian jiedu decoction play a critical role in the treatment of sepsis
por: Chen, Guirong, et al.
Publicado: (2022)

Qingfei Paidu Decoction for COVID-19: A Bibliometric Analysis
por: LIU, Si Hong, et al.
Publicado: (2021)

Molecular mechanism of Ganji Fang in the treatment of hepatocellular carcinoma based on network pharmacology, molecular docking and experimental verification technology
por: Yang, Miaolun, et al.
Publicado: (2023)

Integrating Network Pharmacology and Experimental Validation to Decipher the Mechanism of Action of Huanglian Jiedu Decoction in Treating Atherosclerosis
por: Liang, Jiahua, et al.
Publicado: (2021)

Molecular mechanisms of Huanglian Jiedu decoction in treating Alzheimer’s disease by regulating microbiome via network pharmacology and molecular docking analysis
por: Zheng, Renyuan, et al.
Publicado: (2023)

Network pharmacology and molecular docking to elucidate the mechanism of pulsatilla decoction in the treatment of colon cancer
por: Liu, Huan, et al.
Publicado: (2022)

Exploring the mechanism of Suanzaoren decoction in treatment of insomnia based on network pharmacology and molecular docking
por: Wang, Shuxiao, et al.
Publicado: (2023)

Study on the Mechanism of Huanglian Jiedu Decoction in Treating Dyslipidemia Based on Network Pharmacology
por: Gong, Zhaohui, et al.
Publicado: (2022)

Treatment Effect of Qingfei Paidu Decoction Combined With Conventional Treatment on COVID-19 Patients and Other Respiratory Diseases: A Multi-Center Retrospective Case Series
por: Zong, Xingyu, et al.
Publicado: (2022)

Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation
por: Lin, Lili, et al.
Publicado: (2021)

Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In silico and experimental study
por: Yang, Ruocong, et al.
Publicado: (2020)

Qing-Yi Decoction in the Treatment of Acute Pancreatitis: An Integrated Approach Based on Chemical Profile, Network Pharmacology, Molecular Docking and Experimental Evaluation
por: Wei, Tian-Fu, et al.
Publicado: (2021)

Yuan-Zhi decoction in the treatment of Alzheimer’s disease: An integrated approach based on chemical profiling, network pharmacology, molecular docking and experimental evaluation
por: Wu, Qiong, et al.
Publicado: (2022)

Protective Effects and Mechanisms of Yinchen Linggui Zhugan Decoction in HFD-Induced Nonalcoholic Fatty Liver Disease Rats Based on Network Pharmacology and Experimental Verification
por: Jiang, Hui, et al.
Publicado: (2022)

The potential mechanism of Longsheyangquan Decoction on the treatment of bladder cancer: Systemic network pharmacology and molecular docking
por: Cheng, Zhang, et al.
Publicado: (2022)

Ancient Chinese Medicine Herbal Formula Huanglian Jiedu Decoction as a Neoadjuvant Treatment of Chemotherapy by Improving Diarrhea and Tumor Response
por: Chan, Yau-Tuen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8um1hp8lgg7kofdt4k6qmehnic