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BRAF and MEK Targeted Therapies in Pediatric Central Nervous System Tumors

SIMPLE SUMMARY: This review is divided into two parts. The first analyzes the mechanisms of two important cellular pathways that are involved in tumoral proliferation, differentiation, migration, and angiogenesis: RAS/RAF/MEK/MAPK and PI3K/AKT/mTOR. The second part focuses on the currently available...

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Detalles Bibliográficos
Autores principales:	Talloa, Dario, Triarico, Silvia, Agresti, Pierpaolo, Mastrangelo, Stefano, Attinà, Giorgio, Romano, Alberto, Maurizi, Palma, Ruggiero, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454417/ https://www.ncbi.nlm.nih.gov/pubmed/36077798 http://dx.doi.org/10.3390/cancers14174264

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