Activation of the Anaphase Promoting Complex Reverses Multiple Drug Resistant Cancer in a Canine Model of Multiple Drug Resistant Lymphoma

SIMPLE SUMMARY: Multiple drug resistant cancers develop all too soon in patients who received successful cancer treatment. A lack of treatment options often leaves palliative care as the last resort. We tested whether the insulin sensitizer, metformin, known to have anti-cancer activity, could impac...

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Detalles Bibliográficos
Autores principales: Arnason, Terra G., MacDonald-Dickinson, Valerie, Gaunt, Matthew Casey, Davies, Gerald F., Lobanova, Liubov, Trost, Brett, Gillespie, Zoe E., Waldner, Matthew, Baldwin, Paige, Borrowman, Devon, Marwood, Hailey, Vizeacoumar, Frederick S., Vizeacoumar, Franco J., Eskiw, Christopher H., Kusalik, Anthony, Harkness, Troy A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454423/
https://www.ncbi.nlm.nih.gov/pubmed/36077749
http://dx.doi.org/10.3390/cancers14174215

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