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Correlation between BAP1 Localization, Driver Mutations, and Patient Survival in Uveal Melanoma

SIMPLE SUMMARY: 100 uveal melanomas from the UK were analyzed for molecular biomarkers, including alterations of chromosomes 3 and 8, cellular localization of BAP1, and genes known to be mutated in uveal melanoma. Consistent with earlier studies, loss of nuclear BAP1 (nBAP1) predicted shorter overal...

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Detalles Bibliográficos
Autores principales:	Cole, Yasemin C., Zhang, Yu-Zhi, Gallo, Beatrice, Januszewski, Adam P., Nastase, Anca, Essex, David J., Thaung, Caroline M. H., Cohen, Victoria M. L., Sagoo, Mandeep S., Bowcock, Anne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454448/ https://www.ncbi.nlm.nih.gov/pubmed/36077643 http://dx.doi.org/10.3390/cancers14174105

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