Cargando…

Interrogating Glioma-Associated Microglia and Macrophage Dynamics Under CSF-1R Therapy with Multitracer In Vivo PET/MRI

Glioma-associated microglia and macrophages (GAMMs) are key players in creating an immunosuppressive microenvironment. They can be efficiently targeted by inhibiting the colony-stimulating factor 1 receptor (CSF-1R). We applied noninvasive PET/CT and PET/MRI using (18)F-fluoroethyltyrosine ((18)F-FE...

Descripción completa

Detalles Bibliográficos
Autores principales:	Foray, Claudia, Barca, Cristina, Winkeler, Alexandra, Wagner, Stefan, Hermann, Sven, Schäfers, Michael, Grauer, Oliver M., Zinnhardt, Bastian, Jacobs, Andreas H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Nuclear Medicine 2022
Materias:	Basic Science Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454459/ https://www.ncbi.nlm.nih.gov/pubmed/35115369 http://dx.doi.org/10.2967/jnumed.121.263318

Ejemplares similares

The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke)
por: Barca, Cristina, et al.
Publicado: (2021)

A Longitudinal PET/MRI Study of Colony-Stimulating Factor 1 Receptor–Mediated Microglia Depletion in Experimental Stroke
por: Barca, Cristina, et al.
Publicado: (2022)

In Vivo Quantitative Imaging of Glioma Heterogeneity Employing Positron Emission Tomography
por: Barca, Cristina, et al.
Publicado: (2022)

Imaging temozolomide-induced changes in the myeloid glioma microenvironment
por: Foray, Claudia, et al.
Publicado: (2021)

Short-Term Colony-Stimulating Factor 1 Receptor Inhibition–Induced Repopulation After Stroke Assessed by Longitudinal (18)F-DPA-714 PET Imaging
por: Barca, Cristina, et al.
Publicado: (2022)

PET and the multitracer concept in the study of neurodegenerative diseases
por: Engler, Henry, et al.
Publicado: (2015)

Impact of hydroxytyrosol on stroke: tracking therapy response on neuroinflammation and cerebrovascular parameters using PET-MR imaging and on functional outcomes
por: Barca, Cristina, et al.
Publicado: (2021)

Multitracer model for staging cortical amyloid deposition using PET imaging
por: Collij, Lyduine E., et al.
Publicado: (2020)

Molecular Imaging of Immune Cell Dynamics During De- and Remyelination in the Cuprizone Model of Multiple Sclerosis by [(18)F]DPA-714 PET and MRI
por: Zinnhardt, Bastian, et al.
Publicado: (2019)

Multitrace AdS/CFT and Master Field Dynamics
por: Barbon, J.L.F.
Publicado: (2002)

Multitrace Deformations of Vector and Adjoint Theories and their Holographic Duals
por: Elitzur, S., et al.
Publicado: (2005)

Multimodal Imaging of Patients With Gliomas Confirms (11)C-MET PET as a Complementary Marker to MRI for Noninvasive Tumor Grading and Intraindividual Follow-Up After Therapy
por: Laukamp, Kai R., et al.
Publicado: (2017)

In vivo imaging biomarkers of neuroinflammation in the development and assessment of stroke therapies - towards clinical translation
por: Zinnhardt, Bastian, et al.
Publicado: (2018)

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke
por: Zinnhardt, Bastian, et al.
Publicado: (2015)

Waterline Disinfectants Reduce Dental Bioaerosols: A Multitracer Validation
por: Allison, J.R., et al.
Publicado: (2022)

AdS/CFT, Multitrace Deformations and New Instabilities of Nonlocal String Theories
por: Barbon, J.L.F., et al.
Publicado: (2003)

Initial experience with [(18)F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system
por: Backhaus, Philipp, et al.
Publicado: (2020)

Cholinergic activity and levodopa‐induced dyskinesia: a multitracer molecular imaging study
por: Brumberg, Joachim, et al.
Publicado: (2017)

Deep learning‐guided joint attenuation and scatter correction in multitracer neuroimaging studies
por: Arabi, Hossein, et al.
Publicado: (2020)

An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin
por: Zats, Liat Peretz, et al.
Publicado: (2022)

Glioma-associated microglia/macrophages augment tumorigenicity in canine astrocytoma, a naturally occurring model of human glioma
por: Toedebusch, Ryan, et al.
Publicado: (2021)

The translocator protein ligand [(18)F]DPA-714 images glioma and activated microglia in vivo
por: Winkeler, Alexandra, et al.
Publicado: (2012)

Systematic Interrogation of Angiogenesis in the Ischemic Mouse Hind Limb: Vulnerabilities and Quality Assurance
por: Lee, Jason J., et al.
Publicado: (2020)

Expanding Theranostic Radiopharmaceuticals for Tumor Diagnosis and Therapy
por: Barca, Cristina, et al.
Publicado: (2021)

Multitracer PET/CT with [(18)F]Fluorodeoxiglucose and [(18)F]Fluorocholine in the Initial Staging of Multiple Myeloma Patients Applying the IMPeTus Criteria: A Pilot Study
por: Garrastachu Zumarán, Puy, et al.
Publicado: (2023)

Combined Fluorescence-Guided Resection and Intracavitary Thermotherapy with Superparamagnetic Iron-Oxide Nanoparticles for Recurrent High-Grade Glioma: Case Series with Emphasis on Complication Management
por: Schwake, Michael, et al.
Publicado: (2022)

Towards Optimized Bioavailability of (99m)Tc-Labeled Barbiturates for Non-invasive Imaging of Matrix Metalloproteinase Activity
por: Honold, Lisa, et al.
Publicado: (2021)

Multitracer Stable Isotope Quantification of Arginase and Nitric Oxide Synthase Activity in a Mouse Model of Pseudomonas Lung Infection
por: Grasemann, Hartmut, et al.
Publicado: (2014)

CSF tau and β-amyloid as biomarkers for mild cognitive impairment
por: Hampel, Harald, et al.
Publicado: (2004)

Involvement of the M-CSF/IL-34/CSF-1R pathway in malignant pleural mesothelioma
por: Blondy, Thibaut, et al.
Publicado: (2020)

G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment
por: Martinez Sanz, Paula, et al.
Publicado: (2021)

Mouse Models to Interrogate the Implications of the Differentiation Status in the Ontogeny of Gliomas
por: Muñoz, Diana Marcela, et al.
Publicado: (2011)

Dispersion-corrected extracorporeal arterial input functions in PET studies of mice: a comparison to intracorporeal microprobe measurements
por: Cufe, Juela, et al.
Publicado: (2023)

Intrathecal versus Peripheral Inflammatory Protein Profile in MS Patients at Diagnosis: A Comprehensive Investigation on Serum and CSF
por: Pezzini, Francesco, et al.
Publicado: (2023)

Microglia immunophenotyping in gliomas
por: Annovazzi, Laura, et al.
Publicado: (2018)

Characterization of G-CSF receptor expression in medulloblastoma
por: Paul, Megan Rose, et al.
Publicado: (2020)

Interrogating the immune-modulating roles of radiation therapy for a rational combination with immune-checkpoint inhibitors in treating pancreatic cancer
por: Fujiwara, Kenji, et al.
Publicado: (2020)

Interrogation of IDH1 Status in Gliomas by Fourier Transform Infrared Spectroscopy
por: Cameron, James M., et al.
Publicado: (2020)

Microglia-Derived Microvesicles Affect Microglia Phenotype in Glioma
por: Grimaldi, Alfonso, et al.
Publicado: (2019)

Noninvasive quantification of SIRT1 expression–activity and pharmacologic inhibition in a rat model of intracerebral glioma using 2-[(18)F]BzAHA PET/CT/MRI
por: Laws, Maxwell T, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t5t1o1hevbja754bnqsf7f5tc1