Inhibition of Autophagy Promotes the Anti-Tumor Effect of Metformin in Oral Squamous Cell Carcinoma

SIMPLE SUMMARY: In this study, we found that metformin could inhibit the cell proliferation of Oral Squamous Cell Carcinoma (OSCC) by promoting apoptosis and blocking the cell cycle. Furthermore, inhibiting autophagy with hydroxychloroquine (HCQ) could enhance the anti-tumor effect of metformin in O...

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Detalles Bibliográficos
Autores principales: Zhao, Wei, Chen, Chen, Zhou, Jianjun, Chen, Xiaoqing, Cai, Kuan, Shen, Miaomiao, Chen, Xuan, Jiang, Lei, Wang, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454503/
https://www.ncbi.nlm.nih.gov/pubmed/36077722
http://dx.doi.org/10.3390/cancers14174185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454503/
https://www.ncbi.nlm.nih.gov/pubmed/36077722
http://dx.doi.org/10.3390/cancers14174185

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