Dynamic Expression of EpCAM in Primary and Metastatic Lung Cancer Is Controlled by Both Genetic and Epigenetic Mechanisms

SIMPLE SUMMARY: Epithelial cell adhesion molecule (EpCAM) is a tumor marker widely used in both basic studies and clinics. However, our study demonstrates that EpCAM expression is strongly upregulated by gene amplification and promoter hypomethylation in primary lung tumors, but severely downregulat...

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Detalles Bibliográficos
Autores principales: Cui, Yeting, Li, Jiapeng, Liu, Xiyu, Gu, Lixing, Lyu, Mengqing, Zhou, Jingjiao, Zhang, Xiaoyu, Liu, Yu, Zhu, Haichuan, Zhang, Tongcun, Sun, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454530/
https://www.ncbi.nlm.nih.gov/pubmed/36077658
http://dx.doi.org/10.3390/cancers14174121

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