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Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression
SIMPLE SUMMARY: Nucleolin (NCL) regulates tumour growth and angiogenesis, and its inhibition normalizes tumour vessels and impairs pancreatic ductal adenocarcinoma (PDAC) growth. Since tumour vessel normalization promotes immunostimulatory reprogramming, we investigated the effects of a selective in...
Autores principales: | Ponzo, Matteo, Debesset, Anais, Cossutta, Mélissande, Chalabi-Dchar, Mounira, Houppe, Claire, Pilon, Caroline, Nicolas-Boluda, Alba, Meunier, Sylvain, Raineri, Fabio, Thiolat, Allan, Nicolle, Rémy, Maione, Federica, Brundu, Serena, Cojocaru, Carina Florina, Bouvet, Philippe, Bousquet, Corinne, Gazeau, Florence, Tournigand, Christophe, Courty, José, Giraudo, Enrico, Cohen, José L., Cascone, Ilaria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454580/ https://www.ncbi.nlm.nih.gov/pubmed/36077801 http://dx.doi.org/10.3390/cancers14174265 |
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