The Proteome Signatures of Fibroblasts from Patients with Severe, Intermediate and Mild Spinal Muscular Atrophy Show Limited Overlap

Most research to characterise the molecular consequences of spinal muscular atrophy (SMA) has focused on SMA I. Here, proteomic profiling of skin fibroblasts from severe (SMA I), intermediate (SMA II), and mild (SMA III) patients, alongside age-matched controls, was conducted using SWATH mass spectr...

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Detalles Bibliográficos
Autores principales: Brown, Sharon J., Kline, Rachel A., Synowsky, Silvia A., Shirran, Sally L., Holt, Ian, Sillence, Kelly A., Claus, Peter, Wirth, Brunhilde, Wishart, Thomas M., Fuller, Heidi R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454632/
https://www.ncbi.nlm.nih.gov/pubmed/36078032
http://dx.doi.org/10.3390/cells11172624

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