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Interleukin 4 Controls the Pro-Tumoral Role of Macrophages in Mammary Cancer Pulmonary Metastasis in Mice

SIMPLE SUMMARY: Metastasis is the main cause of death from breast cancer. In mouse models of breast cancer lung metastasis, macrophages enhance metastasis by promoting tumor cell seeding and persistent growth. Here, we show that interleukin-4 (IL4) is required for this process as IL4 receptor (IL4rα...

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Detalles Bibliográficos
Autores principales:	Rodriguez-Tirado, Carolina, Entenberg, David, Li, Jiufeng, Qian, Bin-Zhi, Condeelis, John S., Pollard, Jeffrey W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454655/ https://www.ncbi.nlm.nih.gov/pubmed/36077870 http://dx.doi.org/10.3390/cancers14174336

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