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The Degradation of TMEM166 by Autophagy Promotes AMPK Activation to Protect SH-SY5Y Cells Exposed to MPP(+)

Neuronal oxidative stress caused by mitochondrial dysfunction plays a crucial role in the development of Parkinson’s disease (PD). Growing evidence shows that autophagy confers neuroprotection in oxidative-stress-associated PD. This work aims to investigate the involvement of TMEM166, an endoplasmic...

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Detalles Bibliográficos
Autores principales: Liao, Zhaozhong, Gong, Zunshuang, Wang, Zhe, Yang, Weiyan, Liu, Wenjing, Hou, Lin, Liu, Xiaokun, Hua, Junnan, Wang, Bin, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454683/
https://www.ncbi.nlm.nih.gov/pubmed/36078115
http://dx.doi.org/10.3390/cells11172706

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