TcpC Inhibits M1 but Promotes M2 Macrophage Polarization via Regulation of the MAPK/NF-κB and Akt/STAT6 Pathways in Urinary Tract Infection

ABSTRACT: TcpC is a multifunctional virulence factor of Uropathogenic Escherichia coli (UPEC). Macrophages can differentiate into two different subsets M1 and M2 that play distinct roles in anti-infection immunity. Here, we investigate the influence of TcpC on M1/M2 polarization and the potential me...

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Detalles Bibliográficos
Autores principales: Fang, Jiaqi, Ou, Qian, Wu, Boheng, Li, Sisi, Wu, Mian, Qiu, Jialing, Cen, Nuo, Hu, Kaixin, Che, Yangfei, Ma, Yuan, Pan, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454685/
https://www.ncbi.nlm.nih.gov/pubmed/36078080
http://dx.doi.org/10.3390/cells11172674

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