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Hypermethylation of PRKCZ Regulated by E6 Inhibits Invasion and EMT via Cdc42 in HPV-Related Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: HPV+ and HPV- HNSCC share distinct epigenetic characteristics and clinicopathological features. The aim of our study was to assess whether DNA methylation plays a role in the progression of HPV+ HNSCC. We used a HumanMethylation450 BeadChip array (Illumina) to identify PRKCZ genes ex...

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Detalles Bibliográficos
Autores principales:	Wang, Hao-Fan, Jiang, Jian, Wu, Jia-Shun, Zhang, Mei, Pang, Xin, Dai, Li, Tang, Ya-Ling, Liang, Xin-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454700/ https://www.ncbi.nlm.nih.gov/pubmed/36077689 http://dx.doi.org/10.3390/cancers14174151

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