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P2Y(2)R-Mediated PAK1 Activation Is Involved in ESM-1 Overexpression in RT-R-MDA-MB-231 through FoxO1 Regulation

SIMPLE SUMMARY: Radiotherapy is an important treatment to treat triple-negative breast cancer (TNBC; ER(−), PR(−), HER2(−)) patients. However, the radioresistance of BC cells remains the main obstacle to radiotherapy efficacy, which leads to increased tumor relapse and metastasis. Previously, we dis...

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Detalles Bibliográficos
Autores principales: Jin, Hana, Kim, Hye Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454712/
https://www.ncbi.nlm.nih.gov/pubmed/36077661
http://dx.doi.org/10.3390/cancers14174124

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