PARP Inhibitors for Breast Cancer: Germline BRCA1/2 and Beyond

SIMPLE SUMMARY: Poly-adenosine diphosphate ribose polymerase (PARP) inhibitors (PARPi) are effective against tumors with mutations in DNA repair genes, most commonly in the BRCA1 and BRCA2 genes. Because these tumors are unable to repair their DNA, PARPi have been used to target DNA repair pathways...

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Detalles Bibliográficos
Autores principales: Menezes, Maria Clara Saad, Raheem, Farah, Mina, Lida, Ernst, Brenda, Batalini, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454726/
https://www.ncbi.nlm.nih.gov/pubmed/36077867
http://dx.doi.org/10.3390/cancers14174332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454726/
https://www.ncbi.nlm.nih.gov/pubmed/36077867
http://dx.doi.org/10.3390/cancers14174332

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