A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer’s Disease

In the current study, for the first time, we study mitophagy enhancer urolithin A and a combination of urolithin A+green tea extract EGCG against human Aβ peptide-induced mitochondrial and synaptic, dendritic, inflammatory toxicities and behavioral changes in humanized homozygous amyloid beta knocki...

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Detalles Bibliográficos
Autores principales: Kshirsagar, Sudhir, Alvir, Rainier Vladlen, Pradeepkiran, Jangampalli Adi, Hindle, Ashly, Vijayan, Murali, Ramasubramaniam, Bhagavathi, Kumar, Subodh, Reddy, Arubala P., Reddy, P. Hemachandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454743/
https://www.ncbi.nlm.nih.gov/pubmed/36078067
http://dx.doi.org/10.3390/cells11172660

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