Hepatic, Extrahepatic and Extracellular Vesicle Cytochrome P450 2E1 in Alcohol and Acetaminophen-Mediated Adverse Interactions and Potential Treatment Options

Alcohol and several therapeutic drugs, including acetaminophen, are metabolized by cytochrome P450 2E1 (CYP2E1) into toxic compounds. At low levels, these compounds are not detrimental, but higher sustained levels of these compounds can lead to life-long problems such as cytotoxicity, organ damage,...

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Detalles Bibliográficos
Autores principales: Kumar, Santosh, Singla, Bhupesh, Singh, Ajay K., Thomas-Gooch, Stacey M., Zhi, Kaining, Singh, Udai P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454765/
https://www.ncbi.nlm.nih.gov/pubmed/36078027
http://dx.doi.org/10.3390/cells11172620

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