Cargando…
IRF8: Mechanism of Action and Health Implications
Interferon regulatory factor 8 (IRF8) is a transcription factor of the IRF protein family. IRF8 was originally identified as an essentialfactor for myeloid cell lineage commitment and differentiation. Deletion of Irf8 leads to massive accumulation of CD11b(+)Gr1(+) immature myeloid cells (IMCs), par...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454819/ https://www.ncbi.nlm.nih.gov/pubmed/36078039 http://dx.doi.org/10.3390/cells11172630 |