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IRF8: Mechanism of Action and Health Implications

Interferon regulatory factor 8 (IRF8) is a transcription factor of the IRF protein family. IRF8 was originally identified as an essentialfactor for myeloid cell lineage commitment and differentiation. Deletion of Irf8 leads to massive accumulation of CD11b(+)Gr1(+) immature myeloid cells (IMCs), par...

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Detalles Bibliográficos
Autores principales:	Moorman, Hannah R., Reategui, Yazmin, Poschel, Dakota B., Liu, Kebin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454819/ https://www.ncbi.nlm.nih.gov/pubmed/36078039 http://dx.doi.org/10.3390/cells11172630

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