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MHC Class II Expression Influences the Composition and Distribution of Immune Cells in the Metastatic Colorectal Cancer Microenvironment
SIMPLE SUMMARY: Extensive data exist regarding the importance of major histocompatibility complex (MHC) class I in the tumor microenvironment, but data on MHC class II (MHC-II) are lacking. Using multiplex immunohistochemistry and spatial modeling, we demonstrate that MHC-II expression impacts both...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454847/ https://www.ncbi.nlm.nih.gov/pubmed/36077630 http://dx.doi.org/10.3390/cancers14174092 |