MHC Class II Expression Influences the Composition and Distribution of Immune Cells in the Metastatic Colorectal Cancer Microenvironment

SIMPLE SUMMARY: Extensive data exist regarding the importance of major histocompatibility complex (MHC) class I in the tumor microenvironment, but data on MHC class II (MHC-II) are lacking. Using multiplex immunohistochemistry and spatial modeling, we demonstrate that MHC-II expression impacts both...

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Detalles Bibliográficos
Autores principales: Griffith, Brian D., Turcotte, Simon, Lazarus, Jenny, Lima, Fatima, Bell, Samantha, Delrosario, Lawrence, McGue, Jake, Krishnan, Santhoshi, Oneka, Morgan D., Nathan, Hari, Smith, J. Joshua, D’Angelica, Michael I., Shia, Jinru, Di Magliano, Marina Pasca, Rao, Arvind, Frankel, Timothy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454847/
https://www.ncbi.nlm.nih.gov/pubmed/36077630
http://dx.doi.org/10.3390/cancers14174092

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