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Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells

SIMPLE SUMMARY: Cancer cells undergo metabolic modifications in order to meet their high energetic demand. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcriptional factor primarily known as a xenobiotic sensor. However, this receptor seems to have a wide range of physiological roles...

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Detalles Bibliográficos
Autores principales: Karasová, Martina, Procházková, Jiřina, Tylichová, Zuzana, Fedr, Radek, Ciganek, Miroslav, Machala, Miroslav, Dvořák, Zdeněk, Vyhlídalová, Barbora, Zůvalová, Iveta, Ehrmann, Jiří, Bouchal, Jan, Andrysík, Zdeněk, Vondráček, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454859/
https://www.ncbi.nlm.nih.gov/pubmed/36077780
http://dx.doi.org/10.3390/cancers14174245