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Differential Epigenetic Status and Responses to Stressors between Retinal Cybrids Cells with African versus European Mitochondrial DNA: Insights into Disease Susceptibilities

Mitochondrial (mt) DNA can be classified into haplogroups, which represent populations with different geographic origins. Individuals of maternal African backgrounds (L haplogroup) are more prone to develop specific diseases compared those with maternal European-H haplogroups. Using a cybrid model,...

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Detalles Bibliográficos
Autores principales: Atilano, Shari R., Abedi, Sina, Ianopol, Narcisa V., Singh, Mithalesh K., Norman, J Lucas, Malik, Deepika, Falatoonzadeh, Payam, Chwa, Marilyn, Nesburn, Anthony B., Kuppermann, Baruch D., Kenney, M. Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454894/
https://www.ncbi.nlm.nih.gov/pubmed/36078063
http://dx.doi.org/10.3390/cells11172655

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