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Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs
SIMPLE SUMMARY: Fat is a vital body tissue of pigs and a crucial index that affects the production efficiency of pigs. In this study, Duroc pigs and Luchuan pigs were used as animal materials, transcriptome sequencing was used to compare the back adipose tissue of the two breeds, to explore the key...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454924/ https://www.ncbi.nlm.nih.gov/pubmed/36077979 http://dx.doi.org/10.3390/ani12172258 |
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author | Pan, Hongyuan Huang, Tengda Yu, Lin Wang, Peng Su, Songtao Wu, Tian Bai, Yin Teng, Yonghao Wei, Yutian Zhou, Lei Li, Yixing |
author_facet | Pan, Hongyuan Huang, Tengda Yu, Lin Wang, Peng Su, Songtao Wu, Tian Bai, Yin Teng, Yonghao Wei, Yutian Zhou, Lei Li, Yixing |
author_sort | Pan, Hongyuan |
collection | PubMed |
description | SIMPLE SUMMARY: Fat is a vital body tissue of pigs and a crucial index that affects the production efficiency of pigs. In this study, Duroc pigs and Luchuan pigs were used as animal materials, transcriptome sequencing was used to compare the back adipose tissue of the two breeds, to explore the key reason of difference in fat deposition. The result provided new ideas and reference for further study of fat development. ABSTRACT: Fat deposition is a crucial element in pig production that affects production efficiency, quality and consumer choices. In this study, Duroc pigs, a Western, famous lean pig breed, and Luchuan pigs, a Chinese, native obese pig breed, were used as animal materials. Transcriptome sequencing was used to compare the back adipose tissue of Duroc and Luchuan pigs, to explore the key genes regulating fat deposition. The results showed that 418 genes were highly expressed in the Duroc pig, and 441 genes were highly expressed in the Luchuan pig. In addition, the function enrichment analysis disclosed that the DEGs had been primarily enriched in lipid metabolism, storage and transport pathways. Furthermore, significant differences in the metabolic pathways of alpha-linolenic acid, linoleic acid and arachidonic acid explained the differences in the flavor of the two kinds of pork. Finally, the gene set enrichment analysis (GSEA) exposed that the difference in fat deposition between Duroc and Luchuan pigs may be due to the differential regulation of the metabolism pathway of fatty acid. Therefore, this study described the differential expression transcriptional map of adipose tissue of Duroc pig and Luchuan pig, identified the functional genes regulating pig fat deposition, and provided new hypotheses and references for further study of fat development. |
format | Online Article Text |
id | pubmed-9454924 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94549242022-09-09 Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs Pan, Hongyuan Huang, Tengda Yu, Lin Wang, Peng Su, Songtao Wu, Tian Bai, Yin Teng, Yonghao Wei, Yutian Zhou, Lei Li, Yixing Animals (Basel) Article SIMPLE SUMMARY: Fat is a vital body tissue of pigs and a crucial index that affects the production efficiency of pigs. In this study, Duroc pigs and Luchuan pigs were used as animal materials, transcriptome sequencing was used to compare the back adipose tissue of the two breeds, to explore the key reason of difference in fat deposition. The result provided new ideas and reference for further study of fat development. ABSTRACT: Fat deposition is a crucial element in pig production that affects production efficiency, quality and consumer choices. In this study, Duroc pigs, a Western, famous lean pig breed, and Luchuan pigs, a Chinese, native obese pig breed, were used as animal materials. Transcriptome sequencing was used to compare the back adipose tissue of Duroc and Luchuan pigs, to explore the key genes regulating fat deposition. The results showed that 418 genes were highly expressed in the Duroc pig, and 441 genes were highly expressed in the Luchuan pig. In addition, the function enrichment analysis disclosed that the DEGs had been primarily enriched in lipid metabolism, storage and transport pathways. Furthermore, significant differences in the metabolic pathways of alpha-linolenic acid, linoleic acid and arachidonic acid explained the differences in the flavor of the two kinds of pork. Finally, the gene set enrichment analysis (GSEA) exposed that the difference in fat deposition between Duroc and Luchuan pigs may be due to the differential regulation of the metabolism pathway of fatty acid. Therefore, this study described the differential expression transcriptional map of adipose tissue of Duroc pig and Luchuan pig, identified the functional genes regulating pig fat deposition, and provided new hypotheses and references for further study of fat development. MDPI 2022-08-31 /pmc/articles/PMC9454924/ /pubmed/36077979 http://dx.doi.org/10.3390/ani12172258 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pan, Hongyuan Huang, Tengda Yu, Lin Wang, Peng Su, Songtao Wu, Tian Bai, Yin Teng, Yonghao Wei, Yutian Zhou, Lei Li, Yixing Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs |
title | Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs |
title_full | Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs |
title_fullStr | Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs |
title_full_unstemmed | Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs |
title_short | Transcriptome Analysis of the Adipose Tissue of Luchuan and Duroc Pigs |
title_sort | transcriptome analysis of the adipose tissue of luchuan and duroc pigs |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454924/ https://www.ncbi.nlm.nih.gov/pubmed/36077979 http://dx.doi.org/10.3390/ani12172258 |
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