The Prostaglandin E2 Receptor EP4 Promotes Vascular Neointimal Hyperplasia through Translational Control of Tenascin C via the cAPM/PKA/mTORC1/rpS6 Pathway

Prostaglandin E2 (PGE2) is an important metabolite of arachidonic acid which plays a crucial role in vascular physiology and pathophysiology via its four receptors (EP1-4). However, the role of vascular smooth muscle cell (VSMC) EP4 in neointimal hyperplasia is largely unknown. Here we showed that V...

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Detalles Bibliográficos
Autores principales: Xu, Hu, Fang, Bingying, Bao, Chengzhen, Mao, Xiuhui, Zhu, Chunhua, Ye, Lan, Liu, Qian, Li, Yaqing, Du, Chunxiu, Qi, Hang, Zhang, Xiaoyan, Guan, Youfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9454981/
https://www.ncbi.nlm.nih.gov/pubmed/36078128
http://dx.doi.org/10.3390/cells11172720

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