Immune Determinants of Viral Clearance in Hospitalised COVID-19 Patients: Reduced Circulating Naïve CD4+ T Cell Counts Correspond with Delayed Viral Clearance

Virus-specific cellular and humoral responses are major determinants for protection from critical illness after SARS-CoV-2 infection. However, the magnitude of the contribution of each of the components to viral clearance remains unclear. Here, we studied the timing of viral clearance in relation to...

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Detalles Bibliográficos
Autores principales: Zlei, Mihaela, Sidorov, Igor A., Joosten, Simone A., Heemskerk, Mirjam H. M., Myeni, Sebenzile K., Pothast, Cilia R., de Brouwer, Caroline S., Boomaars-van der Zanden, A. Linda, van Meijgaarden, Krista E., Morales, Shessy T., Wessels, Els, Janse, Jacqueline J., Goeman, Jelle J., Cobbaert, Christa M., Kroes, Aloys C. M., Cannegieter, Suzanne C., Roestenberg, Meta, Visser, Leonardus G., Kikkert, Marjolein, Feltkamp, Mariet C. W., Arbous, Sesmu M., Staal, Frank J. T., Ottenhoff, Tom H. M., van Dongen, Jacques J. M., Roukens, Anna H. E., de Vries, Jutte J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455062/
https://www.ncbi.nlm.nih.gov/pubmed/36078151
http://dx.doi.org/10.3390/cells11172743

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