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Functional Drug Screening of Small Molecule Inhibitors of Epigenetic Modifiers in Refractory AML Patients

SIMPLE SUMMARY: Acute myeloid leukemia is a cancer originating in the bone marrow and peripheral blood. Genetic mutations observed with the disease are difficult to target therapeutically and patients often have different treatment responses to the standard of care. By finding epigenetic compounds t...

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Detalles Bibliográficos
Autores principales: Dennison, Jessica L., Al-Ali, Hassan, Volmar, Claude-Henry, Brothers, Shaun, Watts, Justin, Wahlestedt, Claes, Lohse, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455071/
https://www.ncbi.nlm.nih.gov/pubmed/36077629
http://dx.doi.org/10.3390/cancers14174094