HER2 c-Terminal Fragments Are Expressed via Internal Translation of the HER2 mRNA

The HER2/neu signaling pathway is one of the most frequently mutated in human cancer. Although therapeutics targeting this pathway have good efficacy, cancer cells frequently develop resistance. The HER2 gene encodes the full-length HER2 protein, as well as smaller c-terminal fragments (CTFs), which...

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Detalles Bibliográficos
Autores principales: Godfrey, Jack D., Hejazi, Daniel, Du, Xiaofei, Wei, Cenfu, Rao, Eshaan, Gomez, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455161/
https://www.ncbi.nlm.nih.gov/pubmed/36076950
http://dx.doi.org/10.3390/ijms23179549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455161/
https://www.ncbi.nlm.nih.gov/pubmed/36076950
http://dx.doi.org/10.3390/ijms23179549

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