Cargando…

Pharmacological Inhibition of S100A4 Attenuates Fibroblast Activation and Renal Fibrosis

The TGF-β/Smad3 signaling pathway is an important process in the pathogenesis of kidney fibrosis. However, the molecular mechanisms are not completely elucidated. The current study examined the functional role of S100A4 in regulating TGF-β/Smad3 signaling in fibroblast activation and kidney fibrosis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Jia, Jiao, Baihai, Tran, Melanie, Wang, Yanlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455228/ https://www.ncbi.nlm.nih.gov/pubmed/36078170 http://dx.doi.org/10.3390/cells11172762

Ejemplares similares

Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis
por: Jiao, Baihai, et al.
Publicado: (2021)

STAT6 Deficiency Attenuates Myeloid Fibroblast Activation and Macrophage Polarization in Experimental Folic Acid Nephropathy
por: Jiao, Baihai, et al.
Publicado: (2021)

Pharmacological Inhibition of STING/TBK1 Signaling Attenuates Myeloid Fibroblast Activation and Macrophage to Myofibroblast Transition in Renal Fibrosis
por: Zeng, Haimei, et al.
Publicado: (2022)

Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis
por: Xiong, Chongxiang, et al.
Publicado: (2016)

Role of Bone Marrow-Derived Fibroblasts in Renal Fibrosis
por: Yan, Jingyin, et al.
Publicado: (2016)

Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling
por: Zhang, Lei, et al.
Publicado: (2015)

S100A4(+) Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts
por: Li, Yanan, et al.
Publicado: (2018)

Metformin attenuates fibroblast activation during pulmonary fibrosis by targeting S100A4 via AMPK-STAT3 axis
por: Ji, Huimin, et al.
Publicado: (2023)

S100a4 Is Secreted by Alternatively Activated Alveolar Macrophages and Promotes Activation of Lung Fibroblasts in Pulmonary Fibrosis
por: Zhang, Wei, et al.
Publicado: (2018)

Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis
por: Kasam, Rajesh K, et al.
Publicado: (2020)

Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis
por: Yan, Yanli, et al.
Publicado: (2016)

Smad3 Signaling Activates Bone Marrow-Derived Fibroblasts in Renal Fibrosis
por: Chen, Jiyuan, et al.
Publicado: (2014)

Glycogen synthase kinase-3 inhibition attenuates fibroblast activation and development of fibrosis following renal ischemia-reperfusion in mice
por: Singh, Shailendra P., et al.
Publicado: (2015)

BMPER Ameliorates Renal Fibrosis by Inhibiting Tubular Dedifferentiation and Fibroblast Activation
por: Xie, Ting, et al.
Publicado: (2021)

SDMA attenuates renal tubulointerstitial fibrosis through inhibition of STAT4
por: Wang, Yanzhe, et al.
Publicado: (2023)

Pharmacological and Genetic Inhibition of HDAC4 Alleviates Renal Injury and Fibrosis in Mice
por: Shen, Fengchen, et al.
Publicado: (2022)

Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis
por: Subbaiah, Kadiam C. Venkata, et al.
Publicado: (2023)

CCR2 Regulates the Uptake of Bone Marrow-Derived Fibroblasts in Renal Fibrosis
por: Xia, Yunfeng, et al.
Publicado: (2013)

3,3′-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro
por: Xia, Zun-En, et al.
Publicado: (2018)

Adiponectin Attenuates Lung Fibroblasts Activation and Pulmonary Fibrosis Induced by Paraquat
por: Yao, Rong, et al.
Publicado: (2015)

TRAF6 Suppresses the Development of Pulmonary Fibrosis by Attenuating the Activation of Fibroblasts
por: Min, Jiali, et al.
Publicado: (2022)

Pharmacological inhibition of MDM4 alleviates pulmonary fibrosis
por: Mei, Qianru, et al.
Publicado: (2023)

Fibroblast activation protein activated antifibrotic peptide delivery attenuates fibrosis in mouse models of liver fibrosis
por: Lee, Jaiwoo, et al.
Publicado: (2022)

CXCL16 Deficiency Attenuates Renal Injury and Fibrosis in Salt-Sensitive Hypertension
por: Liang, Hua, et al.
Publicado: (2016)

Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
por: Zheng, Haofeng, et al.
Publicado: (2021)

Blockade of Fibroblast YAP Attenuates Cardiac Fibrosis and Dysfunction Through MRTF-A Inhibition
por: Francisco, Jamie, et al.
Publicado: (2020)

Roles of Epigenetics in Cardiac Fibroblast Activation and Fibrosis
por: Shao, Jingrong, et al.
Publicado: (2022)

The chemokine receptor CXCR6 contributes to recruitment of bone marrow-derived fibroblast precursors in renal fibrosis
por: Xia, Yunfeng, et al.
Publicado: (2014)

SGLT1 Knockdown Attenuates Cardiac Fibroblast Activation in Diabetic Cardiac Fibrosis
por: Lin, Hui, et al.
Publicado: (2021)

FAK Inhibition Attenuates Corneal Fibroblast Differentiation In Vitro
por: Yeung, Vincent, et al.
Publicado: (2021)

TRPM8 deficiency attenuates liver fibrosis through S100A9-HNF4α signaling
por: Liu, Qiang, et al.
Publicado: (2022)

Elevation of S100A4 Expression in Buccal Mucosal Fibroblasts by Arecoline: Involvement in the Pathogenesis of Oral Submucous Fibrosis
por: Yu, Cheng-Chia, et al.
Publicado: (2013)

Immunization with an ApoB-100 Related Peptide Vaccine Attenuates Angiotensin-II Induced Hypertension and Renal Fibrosis in Mice
por: Honjo, Tomoyuki, et al.
Publicado: (2015)

Inhibition of FABP4 attenuates cardiac fibrosis through inhibition of NLRP3 inflammasome activation
por: Zhu, Xi, et al.
Publicado: (2022)

Pre-emptive pharmacological inhibition of fatty acid–binding protein 4 attenuates kidney fibrosis by reprogramming tubular lipid metabolism
por: Chen, Yuting, et al.
Publicado: (2021)

Pomolic Acid Ameliorates Fibroblast Activation and Renal Interstitial Fibrosis through Inhibition of SMAD-STAT Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2018)

RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2
por: Zhang, Jianjian, et al.
Publicado: (2021)

Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis
por: Wu, Aimin, et al.
Publicado: (2021)

Jmjd3/IRF4 axis aggravates myeloid fibroblast activation and m2 macrophage to myofibroblast transition in renal fibrosis
por: Liang, Hua, et al.
Publicado: (2022)

KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis
por: Huang, Chunling, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_34r2a1gl9gae13h26chaobou2b