Cargando…

Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis

Epidemiologic studies have shown associations between periodontitis and rheumatoid arthritis (RA), but a causal relationship has not been established. Citrullination of gingival proteins by human peptidylarginine deiminases (PADs) or PAD from Porphyromonas gingivalis has been proposed to generate au...

Descripción completa

Detalles Bibliográficos
Autores principales:	Massarenti, Laura, Enevold, Christian, Damgaard, Dres, Hansen, Peter Riis, Frisch, Morten, Ødum, Niels, Jacobsen, Søren, Nielsen, Claus Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455246/ https://www.ncbi.nlm.nih.gov/pubmed/36076933 http://dx.doi.org/10.3390/ijms23179536

Ejemplares similares

PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking
por: Massarenti, Laura, et al.
Publicado: (2021)

Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase
por: Damgaard, Dres, et al.
Publicado: (2017)

Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery
por: Vejlstrup, Anne, et al.
Publicado: (2019)

Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase
por: Damgaard, Dres, et al.
Publicado: (2016)

Increased levels of peptidylarginine deiminase 2 in synovial fluid from anti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers
por: Damgaard, Dres, et al.
Publicado: (2016)

Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen
por: Damgaard, Dres, et al.
Publicado: (2014)

Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4
por: Martín Monreal, María Teresa, et al.
Publicado: (2021)

Analysis of the peptidylarginine deiminase V gene in rheumatoid arthritis
por: Caponi, L, et al.
Publicado: (2003)

Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3
por: Damgaard, Dres, et al.
Publicado: (2018)

Anti-peptidylarginine deiminase-4 antibodies at mucosal sites can activate peptidylarginine deiminase-4 enzyme activity in rheumatoid arthritis
por: Demoruelle, M. Kristen, et al.
Publicado: (2021)

Features of the citrullinating peptidylarginine deiminase enzymes
por: Vossenaar, ER, et al.
Publicado: (2004)

Peptidylarginine deiminase isoforms expressed in the synovial membrane of rheumatoid arthritis patients
por: Chapuy-Regaud, S, et al.
Publicado: (2003)

Porphyromonas gingivalis in saliva associates with chronic and aggressive periodontitis
por: Damgaard, Christian, et al.
Publicado: (2019)

Functional haplotypes in citrullinating enzyme peptidylarginine deiminase 4 are associated with rheumatoid arthritis
por: Yamamoto, K, et al.
Publicado: (2003)

Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?
por: Mangat, Pamela, et al.
Publicado: (2010)

Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis
por: Cappelli, Laura C., et al.
Publicado: (2018)

Autoantibodies to Peptidylarginine Deiminase 2 Are Associated With Less Severe Disease in Rheumatoid Arthritis
por: Darrah, Erika, et al.
Publicado: (2018)

Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis
por: Montgomery, Anna B, et al.
Publicado: (2016)

Putative Roles for Peptidylarginine Deiminases in COVID-19
por: Arisan, Elif Damla, et al.
Publicado: (2020)

In vivo expression of peptidylarginine deiminase in Drosophila melanogaster
por: Mahneva, Olena, et al.
Publicado: (2020)

Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
por: Méchin, Marie-Claire, et al.
Publicado: (2020)

Expression of Peptidylarginine Deiminase Type 4 in Ovarian Tumors
por: Wang, Lin, et al.
Publicado: (2010)

Role of peptidylarginine deiminase type 4 in gastric cancer
por: Xin, Jiang, et al.
Publicado: (2016)

Peptidylarginine Deiminases as Drug Targets in Neonatal Hypoxic–Ischemic Encephalopathy
por: Lange, Sigrun
Publicado: (2016)

The peptidylarginine deiminase gene is a conserved feature of Porphyromonas gingivalis
por: Gabarrini, Giorgio, et al.
Publicado: (2015)

Peptidylarginine deiminase 4 promotes age-related organ fibrosis
por: Martinod, Kimberly, et al.
Publicado: (2017)

Candida albicans-Induced NETosis Is Independent of Peptidylarginine Deiminase 4
por: Guiducci, Eva, et al.
Publicado: (2018)

Myeloid-Specific Deletion of Peptidylarginine Deiminase 4 Mitigates Atherosclerosis
por: Liu, Yudong, et al.
Publicado: (2018)

Microglial expression of peptidylarginine deiminase 2 in the prenatal rat brain
por: Asaga, Hiroaki, et al.
Publicado: (2007)

Peptidylarginine Deiminase 2 in Murine Antiviral and Autoimmune Antibody Responses
por: Mergaert, Aisha M., et al.
Publicado: (2022)

Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice
por: Sodré, Fernanda M.C., et al.
Publicado: (2021)

Factors Associated with Promoted Proliferation of Osteosarcoma by Peptidylarginine Deiminase 4
por: Guo, Jianping, et al.
Publicado: (2021)

Peptidylarginine Deiminase 2 in Host Immunity: Current Insights and Perspectives
por: Wu, Zhenyu, et al.
Publicado: (2021)

Autocitrullination confers monocyte chemotactic properties to peptidylarginine deiminase 4
por: Yoshida, Ken, et al.
Publicado: (2023)

Porphyromonas gingivalis Peptidylarginine Deiminase, a Key Contributor in the Pathogenesis of Experimental Periodontal Disease and Experimental Arthritis
por: Gully, Neville, et al.
Publicado: (2014)

Peptidylarginine Deiminase Autoimmunity and the Development of Anti–Citrullinated Protein Antibody in Rheumatoid Arthritis: The Hapten–Carrier Model
por: Auger, Isabelle, et al.
Publicado: (2020)

Oral Biofilms from Symbiotic to Pathogenic Interactions and Associated Disease –Connection of Periodontitis and Rheumatic Arthritis by Peptidylarginine Deiminase
por: Kriebel, Katja, et al.
Publicado: (2018)

Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis
por: Engström, Marianne, et al.
Publicado: (2018)

Functional Role of Dimerization of Human Peptidylarginine Deiminase 4 (PAD4)
por: Liu, Yi-Liang, et al.
Publicado: (2011)

Peptidylarginine deiminase type 2 is over expressed in the glaucomatous optic nerve
por: Cafaro, Thamara A., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_2tpne8lhcm5nvumcvai17g4qcq