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Targeting HDAC6 to Overcome Autophagy-Promoted Anti-Cancer Drug Resistance
Histone deacetylases (HDACs) regulate gene expression through the epigenetic modification of chromatin structure. HDAC6, unlike many other HDACs, is present in the cytoplasm. Its deacetylates non-histone proteins and plays diverse roles in cancer cell initiation, proliferation, autophagy, and anti-c...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455701/ https://www.ncbi.nlm.nih.gov/pubmed/36076996 http://dx.doi.org/10.3390/ijms23179592 |