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Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective

The successful application of honey in wound care management has been achieved due to honey’s potent antibacterial effects, characterised by its multifactorial action. Impressive clinical efficacy has ignited its further use in diverse clinical disciplines, including stomatology. Indeed, there is in...

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Detalles Bibliográficos
Autores principales: Deglovic, Juraj, Majtanova, Nora, Majtan, Juraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455747/
https://www.ncbi.nlm.nih.gov/pubmed/36076855
http://dx.doi.org/10.3390/foods11172670
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author Deglovic, Juraj
Majtanova, Nora
Majtan, Juraj
author_facet Deglovic, Juraj
Majtanova, Nora
Majtan, Juraj
author_sort Deglovic, Juraj
collection PubMed
description The successful application of honey in wound care management has been achieved due to honey’s potent antibacterial effects, characterised by its multifactorial action. Impressive clinical efficacy has ignited its further use in diverse clinical disciplines, including stomatology. Indeed, there is increasing usage of honey in dental medicine as a preventive or therapeutic remedy for some periodontal diseases mainly associated with bacteria, such as dental caries, gingivitis and mucositides. Dental caries is undoubtedly a major oral health problem worldwide, with an increasing tendency of incidence. The purpose of this perspective review is to describe the recent progress in the laboratory and clinical use of honey in the prevention of dental caries, with emphasis on the antibacterial and antibiofilm effects of honey. The role of honey in the cariogenic process is also discussed. In addition, the quality of honey and the urgent in vitro evaluation of its antibacterial/antibiofilm properties before clinical use are highlighted. Findings based on data extracted from laboratory studies demonstrate the pronounced antibacterial effect of different honeys against a number of periodontal pathogens, including Streptococcus mutans. Although the promising antibiofilm effects of honey have been reported mainly against S. mutans, these results are limited to very few studies. From a clinical point of view, honey significantly reduces dental plaque; however, it is not superior to the conventional agent. Despite the positive in vitro results, the clinical effectiveness of honey in the prevention of dental caries remains inconclusive since further robust clinical studies are needed.
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spelling pubmed-94557472022-09-09 Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective Deglovic, Juraj Majtanova, Nora Majtan, Juraj Foods Review The successful application of honey in wound care management has been achieved due to honey’s potent antibacterial effects, characterised by its multifactorial action. Impressive clinical efficacy has ignited its further use in diverse clinical disciplines, including stomatology. Indeed, there is increasing usage of honey in dental medicine as a preventive or therapeutic remedy for some periodontal diseases mainly associated with bacteria, such as dental caries, gingivitis and mucositides. Dental caries is undoubtedly a major oral health problem worldwide, with an increasing tendency of incidence. The purpose of this perspective review is to describe the recent progress in the laboratory and clinical use of honey in the prevention of dental caries, with emphasis on the antibacterial and antibiofilm effects of honey. The role of honey in the cariogenic process is also discussed. In addition, the quality of honey and the urgent in vitro evaluation of its antibacterial/antibiofilm properties before clinical use are highlighted. Findings based on data extracted from laboratory studies demonstrate the pronounced antibacterial effect of different honeys against a number of periodontal pathogens, including Streptococcus mutans. Although the promising antibiofilm effects of honey have been reported mainly against S. mutans, these results are limited to very few studies. From a clinical point of view, honey significantly reduces dental plaque; however, it is not superior to the conventional agent. Despite the positive in vitro results, the clinical effectiveness of honey in the prevention of dental caries remains inconclusive since further robust clinical studies are needed. MDPI 2022-09-02 /pmc/articles/PMC9455747/ /pubmed/36076855 http://dx.doi.org/10.3390/foods11172670 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Deglovic, Juraj
Majtanova, Nora
Majtan, Juraj
Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective
title Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective
title_full Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective
title_fullStr Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective
title_full_unstemmed Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective
title_short Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective
title_sort antibacterial and antibiofilm effect of honey in the prevention of dental caries: a recent perspective
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455747/
https://www.ncbi.nlm.nih.gov/pubmed/36076855
http://dx.doi.org/10.3390/foods11172670
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