Cargando…
IL10 Secretion Endows Intestinal Human iNKT Cells with Regulatory Functions Towards Pathogenic T Lymphocytes
BACKGROUND AND AIMS: Invariant natural killer T [iNKT] cells perform pleiotropic functions in different tissues by secreting a vast array of pro-inflammatory and cytotoxic molecules. However, the presence and function of human intestinal iNKT cells capable of secreting immunomodulatory molecules suc...
Autores principales: | Burrello, Claudia, Strati, Francesco, Lattanzi, Georgia, Diaz-Basabe, Angelica, Mileti, Erika, Giuffrè, Maria Rita, Lopez, Gianluca, Cribiù, Fulvia Milena, Trombetta, Elena, Kallikourdis, Marinos, Cremonesi, Marco, Conforti, Francesco, Botti, Fiorenzo, Porretti, Laura, Rescigno, Maria, Vecchi, Maurizio, Fantini, Massimo C, Caprioli, Flavio, Facciotti, Federica |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455792/ https://www.ncbi.nlm.nih.gov/pubmed/35358301 http://dx.doi.org/10.1093/ecco-jcc/jjac049 |
Ejemplares similares
-
Mucosa-associated microbiota drives pathogenic functions in IBD-derived intestinal iNKT cells
por: Burrello, Claudia, et al.
Publicado: (2019) -
License to Kill: When iNKT Cells Are Granted the Use of Lethal Cytotoxicity
por: Díaz-Basabe, Angélica, et al.
Publicado: (2020) -
Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin–granzyme pathway
por: Díaz‐Basabe, Angélica, et al.
Publicado: (2021) -
Antibiotic-associated dysbiosis affects the ability of the gut microbiota to control intestinal inflammation upon fecal microbiota transplantation in experimental colitis models
por: Strati, Francesco, et al.
Publicado: (2021) -
Fecal Microbiota Transplantation Controls Murine Chronic Intestinal Inflammation by Modulating Immune Cell Functions and Gut Microbiota Composition
por: Burrello, Claudia, et al.
Publicado: (2019)