The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation

Multiple sclerosis (MS) is a highly prevalent demyelinating autoimmune condition; the mechanisms regulating its severity and progression are unclear. The IL-17-producing Th17 subset of T cells has been widely implicated in MS and in the mouse model, experimental autoimmune encephalomyelitis (EAE). H...

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Detalles Bibliográficos
Autores principales: Smith, Katie J., Minns, Danielle, McHugh, Brian J., Holloway, Rebecca K., O’Connor, Richard, Williams, Anna, Melrose, Lauren, McPherson, Rhoanne, Miron, Veronique E., Davidson, Donald J., Gwyer Findlay, Emily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455863/
https://www.ncbi.nlm.nih.gov/pubmed/36026478
http://dx.doi.org/10.1371/journal.pbio.3001554

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