Cargando…
Monoclonal Antibody Engineering and Design to Modulate FcRn Activities: A Comprehensive Review
Understanding the biological mechanisms underlying the pH-dependent nature of FcRn binding, as well as the various factors influencing the affinity to FcRn, was concurrent with the arrival of the first recombinant IgG monoclonal antibodies (mAbs) and IgG Fc-fusion proteins in clinical practice. IgG...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455995/ https://www.ncbi.nlm.nih.gov/pubmed/36077002 http://dx.doi.org/10.3390/ijms23179604 |