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Immobilization of Wnt Fragment Peptides on Magnetic Nanoparticles or Synthetic Surfaces Regulate Wnt Signaling Kinetics

Wnt signaling plays an important role in embryogenesis and adult stem cell homeostasis. Its diminished activation is implicated in osteoporosis and degenerative neural diseases. However, systematic administration of Wnt-signaling agonists carries risk, as aberrantly activated Wnt/β-catenin signaling...

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Detalles Bibliográficos
Autores principales: Hu, Bin, Rotherham, Michael, Farrow, Neil, Roach, Paul, Dobson, Jon, El Haj, Alicia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456016/
https://www.ncbi.nlm.nih.gov/pubmed/36077561
http://dx.doi.org/10.3390/ijms231710164