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Interdomain Linker Effect on the Mechanical Stability of Ig Domains in Titin
Titin is the largest protein in humans, composed of more than one hundred immunoglobulin (Ig) domains, and plays a critical role in muscle’s passive elasticity. Thus, the molecular design of this giant polyprotein is responsible for its mechanical function. Interestingly, most of these Ig domains ar...
Autores principales: | Tong, Bei, Tian, Fang, Zheng, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456048/ https://www.ncbi.nlm.nih.gov/pubmed/36077234 http://dx.doi.org/10.3390/ijms23179836 |
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