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Prefrontal Cortical Control of Activity in Nucleus Accumbens Core Is Weakened by High-Fat Diet and Prevented by Co-Treatment with N-Acetylcysteine: Implications for the Development of Obesity

A loss of neuroplastic control on nucleus accumbens (NAc) neuronal activity exerted by the medial prefrontal cortex (mPFC) through long-term depression (LTD) is involved in triggering drug-seeking behavior and relapse on several substances of abuse due to impaired glutamate homeostasis in tripartite...

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Detalles Bibliográficos
Autores principales:	Morgan, Carlos, Sáez-Briones, Patricio, Barra, Rafael, Reyes, Andrea, Zepeda-Morales, Katherine, Constandil, Luis, Ríos, Miguel, Ramírez, Paulina, Burgos, Héctor, Hernández, Alejandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456091/ https://www.ncbi.nlm.nih.gov/pubmed/36077493 http://dx.doi.org/10.3390/ijms231710089

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