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DNA Motifs and an Accessory CRISPR Factor Determine Cas1 Binding and Integration Activity in Sulfolobus islandicus

CRISPR-Cas systems empower prokaryotes with adaptive immunity against invasive mobile genetic elements. At the first step of CRISPR immunity adaptation, short DNA fragments from the invaders are integrated into CRISPR arrays at the leader-proximal end. To date, the mechanism of recognition of the le...

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Detalles Bibliográficos
Autores principales:	Liu, Tao, Xu, Ying, Wang, Xiaojie, Ye, Qing, Liu, Zhenzhen, Zhang, Zhufeng, Liu, Jilin, Yang, Yudong, Peng, Xu, Peng, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456107/ https://www.ncbi.nlm.nih.gov/pubmed/36077578 http://dx.doi.org/10.3390/ijms231710178

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