Optimization of Signal Peptide via Site-Directed Mutagenesis for Enhanced Secretion of Heterologous Proteins in Lactococcus lactis

Secretion efficiency of heterologous proteins in the Generally Regarded As Safe (GRAS) Lactococcus lactis is often reported to be insufficiently low due to limitations such as poor targeting and translocation by the signal peptide or degradation by the host proteases. In this study, the secretion ef...

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Detalles Bibliográficos
Autores principales: Alias, Nur Aqlili Riana, Song, Adelene Ai-Lian, Alitheen, Noorjahan Banu, Rahim, Raha Abdul, Othman, Siti Sarah, In, Lionel Lian Aun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456127/
https://www.ncbi.nlm.nih.gov/pubmed/36077441
http://dx.doi.org/10.3390/ijms231710044

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