The Ambivalence of Connexin43 Gap Peptides in Cardioprotection of the Isolated Heart against Ischemic Injury

The present study investigates infarct-reducing effects of blocking ischemia-induced opening of connexin43 hemichannels using peptides Gap19, Gap26 or Gap27. Cardioprotection by ischemic preconditioning (IPC) and Gap peptides was compared, and combined treatment was tested in isolated, perfused male...

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Detalles Bibliográficos
Autores principales: Falck, Aleksander Tank, Lund, Bjarte Aarmo, Johansen, David, Lund, Trine, Ytrehus, Kirsti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456187/
https://www.ncbi.nlm.nih.gov/pubmed/36077595
http://dx.doi.org/10.3390/ijms231710197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456187/
https://www.ncbi.nlm.nih.gov/pubmed/36077595
http://dx.doi.org/10.3390/ijms231710197

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