Cargando…

Rosavin Ameliorates Hepatic Inflammation and Fibrosis in the NASH Rat Model via Targeting Hepatic Cell Death

Background: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of chronic liver disease that urgently needs effective therapy. Rosavin, a major constituent of the Rhodiola Rosea plant of the family Crassulaceae, is believed to exhibit multiple pharmacological effects on divers...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albadawy, Reda, Hasanin, Amany Helmy, Agwa, Sara H. A., Hamady, Shaimaa, Aboul-Ela, Yasmin M., Raafat, Mona Hussien, Kamar, Samaa Samir, Othman, Mohamed, Yahia, Yahia A., Matboli, Marwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456245/ https://www.ncbi.nlm.nih.gov/pubmed/36077546 http://dx.doi.org/10.3390/ijms231710148

Ejemplares similares

Prospective insight into the role of benzyl propylene glycoside as a modulator of the cGAS-STING signaling pathway in the management of nonalcoholic fatty pancreas animal model
por: Albadawy, Reda, et al.
Publicado: (2023)

Clinical Significance of HSPD1/MMP14/ITGB1/miR-6881-5P/Lnc-SPARCL1-1:2 RNA Panel in NAFLD/NASH Diagnosis: Egyptian Pilot Study
por: Albadawy, Reda, et al.
Publicado: (2021)

Circulatory Endothelin 1-Regulating RNAs Panel: Promising Biomarkers for Non-Invasive NAFLD/NASH Diagnosis and Stratification: Clinical and Molecular Pilot Study
por: Albadawy, Reda, et al.
Publicado: (2021)

Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study
por: Hasanin, Amany Helmy, et al.
Publicado: (2021)

Modulation of hepatic stellate cells by Mutaflor(®) probiotic in non-alcoholic fatty liver disease management
por: Hany, Noha M., et al.
Publicado: (2022)

Evaluation of the role of kefir in management of non-alcoholic steatohepatitis rat model via modulation of NASH linked mRNA-miRNA panel
por: Salah, Noha, et al.
Publicado: (2023)

mRNA-miRNA-lncRNA Regulatory Network in Nonalcoholic Fatty Liver Disease
por: Matboli, Marwa, et al.
Publicado: (2021)

Identifying SARS-CoV-2 Lineage Mutation Hallmarks and Correlating Them With Clinical Outcomes in Egypt: A Pilot Study
por: Agwa, Sara H. A., et al.
Publicado: (2022)

Hepatic Stellate Cell-Immune Interactions in NASH
por: Carter, James K., et al.
Publicado: (2022)

Cyanidin 3-glucoside modulated cell cycle progression in liver precancerous lesion, in vivo study
por: Matboli, Marwa, et al.
Publicado: (2021)

Transcriptional regulation of Hepatic Stellate Cell activation in NASH
por: Marcher, Ann-Britt, et al.
Publicado: (2019)

Biotransformation of cinnamyl alcohol to rosavins by non-transformed wild type and hairy root cultures of Rhodiola kirilowii
por: Grech-Baran, Marta, et al.
Publicado: (2013)

A probiotic complex, rosavin, zinc, and prebiotics ameliorate intestinal inflammation in an acute colitis mouse model
por: Park, Jin-Sil, et al.
Publicado: (2018)

Exercise of high intensity ameliorates hepatic inflammation and the progression of NASH
por: Fredrickson, Gavin, et al.
Publicado: (2021)

Production, Exacerbating Effect, and EV-Mediated Transcription of Hepatic CCN2 in NASH: Implications for Diagnosis and Therapy of NASH Fibrosis
por: Li, Xinlei, et al.
Publicado: (2023)

Phytochemical and anti-neuropathic investigations of Crocus sativus via alleviating inflammation, oxidative stress and pancreatic beta-cells regeneration
por: Raafat, Karim, et al.
Publicado: (2019)

Analysis of mRNA-miRNA-lncRNA differential expression in prediabetes/type 2 diabetes mellitus patients as potential players in insulin resistance
por: Ali, Hebatalla Said, et al.
Publicado: (2023)

NAFLD and NASH in HCV Infection: Prevalence and Significance in Hepatic and Extrahepatic Manifestations
por: Adinolfi, Luigi Elio, et al.
Publicado: (2016)

Macrophage Stimulating Protein Enhances Hepatic Inflammation in a NASH Model
por: Li, Jieyi, et al.
Publicado: (2016)

Targeting Extracellular RNA Mitigates Hepatic Lipotoxicity and Liver Injury in NASH
por: Tewari, Archana, et al.
Publicado: (2023)

Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH)
por: Vandel, Jimmy, et al.
Publicado: (2020)

Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH
por: Wang, Haiguang, et al.
Publicado: (2023)

Rosavin: Research Advances in Extraction and Synthesis, Pharmacological Activities and Therapeutic Effects on Diseases of the Characteristic Active Ingredients of Rhodiola rosea L.
por: Wang, Shen, et al.
Publicado: (2023)

Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH
por: Escutia-Gutiérrez, Rebeca, et al.
Publicado: (2021)

5-HT(1A) receptors mediate the analgesic effect of rosavin in a mouse model of oxaliplatin-induced peripheral neuropathic pain
por: Li, Daxian, et al.
Publicado: (2021)

Qualitative and Quantitative Evaluation of Rosavin, Salidroside, and p-Tyrosol in Artic Root Products via TLC-Screening, HPLC-DAD, and NMR Spectroscopy
por: Nikolaichuk, Hanna, et al.
Publicado: (2022)

Lamotrigine Decreased Hippocampal Damage and Improved Vascular Risk Markers in a Rat Model of Pentylenetetrazole Induced Kindling Seizure
por: Haggag, Basma S, et al.
Publicado: (2014)

The role of pmrCAB genes in colistin-resistant Acinetobacter baumannii
por: Seleim, Shaimaa Mohamed, et al.
Publicado: (2022)

Identification of a Multi-Messenger RNA Signature as Type 2 Diabetes Mellitus Candidate Genes Involved in Crosstalk between Inflammation and Insulin Resistance
por: Ali, Hebatalla Said, et al.
Publicado: (2022)

Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH
por: Bruschi, Francesca V., et al.
Publicado: (2020)

Hepatic Stellate Cell Activation and Inactivation in NASH-Fibrosis—Roles as Putative Treatment Targets?
por: Zisser, Alexandra, et al.
Publicado: (2021)

MAFLD/NAFLD Biopsy-Free Scoring Systems for Hepatic Steatosis, NASH, and Fibrosis Diagnosis
por: Segura-Azuara, Nancy de los Ángeles, et al.
Publicado: (2022)

An optimized protocol for isolation of hepatic leukocytes retrieved from murine and NASH liver biopsies
por: Bahrami, Ehsan, et al.
Publicado: (2023)

Validation of Hepa-index as a non-invasive biomarkers panel for assessment of hepatic fibrosis in Egyptians with chronic hepatitis C
por: Alboraie, Mohamed, et al.
Publicado: (2017)

Gastroprotective effects of nebivolol and simvastatin against cold restraint stress-induced gastric ulcer in rats
por: Kamar, Samaa Samir, et al.
Publicado: (2020)

Both Elafibranor and Liraglutide Improve NAFLD / NASH but Affect Differentially the Hepatic Lipidome and Metabolome in a Diet-Induced Obese and Biopsy-Confirmed Mouse Model of NASH
por: Perakakis, Nikolaos, et al.
Publicado: (2021)

Egy-Score as a Noninvasive Score for the Assessment of Hepatic Fibrosis in Chronic Hepatitis C: A Preliminary Approach
por: Alboraie, Mohamed, et al.
Publicado: (2014)

Cyanidin-3-Glucoside Modulates hsa_circ_0001345/miRNA106b/ATG16L1 Axis Expression as a Potential Protective Mechanism against Hepatocellular Carcinoma
por: Zabady, Shaimaa, et al.
Publicado: (2022)

Increased α-Fetoprotein Predicts Steatosis among Patients with Chronic Hepatitis C Genotype 4
por: Mousa, Nasser, et al.
Publicado: (2012)

Parasternal intercostal muscle thickening as a predictor of non-invasive ventilation failure in patients with COVID-19
por: Helmy, Mina Adlof, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gp3gg54dhs5o9pt94k78801u4j